Glutaraldehyde 50%
Certificate Of Analysis
Product Name: Glutaraldehyde 50%
| Sample date | 2024.07.09 | Report No. | 20240709 |
| Batch No | 20240709 | Quantity | 17.6MT |
| Test Date | 2024.07.09 | Package | 220kg/drum |
| Items | Specifications | Test Result | |
| Appearance | Colorless or yellowish transparent liquid | Colorless transparent liquid | |
| Purity | 50%min | 50.6% | |
| Methanol，% | 0.5%max | 0.32 | |
| Hazen | 30 max | 15 | |
| Specific Gravity，g/cm3 | 1.126~1.135 g/cm3 | 1.130 | |
| PH | 3.0~5.0 | 3.76 | |
| Result | Qualified | ||
Glutaraldehyde 50% (Pharm grade) Solution Technical Data Sheet
Glutaraldehyde (C₅H₈O₂)
Chemical Formula: OCH(CH₂)₃CHO
Molar Mass: 100.12 g/mol
Appearance: Clear, colorless to yellowish liquid
Odor: Pungent, sharp
Solubility: Miscible with water, alcohol, and organic solvents.
Key Properties:
- Bifunctional Aldehyde: Contains two reactive aldehyde groups (–CHO).
- High Reactivity: Crosslinks proteins, amines, and other nucleophiles.
- Polymerization: Can form cyclic hemiacetals or polymers in water.
- Disinfectant Activity: Effective against bacteria, viruses, fungi, and spores.
- pH-Dependent Stability:
- Acidic pH (pH 3–4): More stable but less biocidal.
- Alkaline pH (pH 7.5–8.5): More reactive but degrades faster.
Uses of Glutaraldehyde:
- Disinfection & Sterilization (Cold Sterilant):
- Used in hospitals for endoscopes, surgical instruments, and dialysis equipment (e.g., Cidex®).
- Effective against Mycobacterium tuberculosis, HIV, and hepatitis B/C.
- Fixative in Microscopy & Histology:
- Preserves biological tissues by crosslinking proteins (alternative to formaldehyde).
- Water Treatment:
- Biocide in oilfield and cooling tower systems.
- Tanning & Leather Processing:
- Crosslinks collagen fibers for durable leather.
- Biotechnology:
- Immobilizes enzymes and stabilizes vaccines.
Safety & Handling:
- Toxicity:
- Irritant: Causes severe eye/skin burns, respiratory issues.
- Sensitizer: Can trigger asthma or allergic reactions.
- Exposure Limits:
- OSHA PEL (Permissible Exposure Limit): 0.2 ppm (8-hour TWA).
- Protective Measures:
- Use in fume hoods with gloves (nitrile/neoprene) and goggles.
- Avoid inhalation; wear a NIOSH-approved respirator if needed.
- Storage:
- Tightly sealed in amber glass or plastic, away from light and heat.
Comparison with Formaldehyde:
| Property | Glutaraldehyde | Formaldehyde |
|---|---|---|
| Structure | Dialdehyde (C₅) | Monoaldehyde (C₁) |
| Fixation | Slower penetration | Faster penetration |
| Toxicity | Less volatile | Highly volatile |
| Sterilization | Better for heat-sensitive tools | Less effective |
Deactivation & Disposal:
- Neutralize with sodium bisulfite (NaHSO₃) before disposal.
- Follow local regulations for hazardous waste.
